KMID : 0378120010280010013
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Chungnam Medical Journal 2001 Volume.28 No. 1 p.13 ~ p.22
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BrdU-induced Fragile Sites Expression in peripheral Blood Lymphocytes of in Stomach Cancer Patients
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Yoon Sook-Ja
Han Seung-Ro Jeong Ok Kim Soo-Il Park Kyung-Ran Lee Young-Ho Kim Won-Sik
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Abstract
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The expression frequency of BrdU-induced fragile sites was examined in stomach cancer patients to determine whether this parameter could be used as a marker of genetic susceptibility in at-risk individuals. G banding performed to detect fragile sites. No difference was found in expression frequency between the stomach cancer patients and a group of normal individuals(p=0.7). This indicates that the expression frequency of BrdU-induced fragile sites is not a suitable marker for assessing genetic susceptibility in stomach cancer patiens.
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KEYWORD
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stomach cancer, BrdU, Fragile site
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